টেমপ্লেট:Diseases of RBCs and megakaryocytes

উইকিপিডিয়া, মুক্ত বিশ্বকোষ থেকে

(টেমপ্লেট:রক্তবিদ্যা থেকে ঘুরে এসেছে)

ঝাঁপ দাও: পরিভ্রমণ, অনুসন্ধান

Pathology: hematology · hematologic diseases of RBCs and megakaryocytes /MEP(D50-69,74,280-287)

Red
blood cells

↑

Poly- cythemia	Polycythemia vera

↓

Micro-: Iron deficiency anemia (Plummer-Vinson syndrome)

Macro-: Megaloblastic anemia (Pernicious anemia)

Hemolytic
(mostly Normo-)

Hereditary	enzymopathy: G6PD · glycolysis (PK, TI, HK) hemoglobinopathy: Thalassemia (alpha, beta, delta) · Sickle-cell disease/trait · HPFH membrane: Hereditary spherocytosis(Minkowski-Chauffard syndrome) · Hereditary elliptocytosis (Southeast Asian ovalocytosis) · Hereditary stomatocytosis

Acquired	Autoimmune (WAHA, CAD, PCH) membrane (PNH) MAHA · TM (HUS) Drug-induced autoimmune · Drug-induced nonautoimmune Hemolytic disease of the newborn

Aplastic
(mostly Normo-)

Hereditary: Fanconi anemia · Diamond–Blackfan anemia

Acquired: PRCA · Sideroblastic anemia · Myelophthisic

MCV (Normocytic, Microcytic, Macrocytic) · MCHC (Normochromic,Hypochromic)

Other

Methemoglobinemia · Sulfhemoglobinemia · Reticulocytopenia

Coagulation/
coagulopathy

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Hyper- coagulability	primary: Antithrombin III deficiency · Protein C deficiency/Activated protein C resistance/Protein S deficiency/Factor V Leiden · Prothrombin G20210A acquired:Thrombocytosis(essential) · DIC (Congenital afibrinogenemia,Purpura fulminans) · autoimmune (Antiphospholipid)

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Hypo-
coagulability

Thrombocytopenia	Thrombocytopenic purpura: ITP (Evans syndrome) · TM (TTP) Heparin-induced thrombocytopenia · May-Hegglin anomaly

Platelet function	adhesion (Bernard–Soulier syndrome) · aggregation (Glanzmann's thrombasthenia) · platelet storage pool deficiency (Hermansky–Pudlak syndrome, Gray platelet syndrome)

Clotting factor	Hemophilia (A/VIII, B/IX, C/XI) • von Willebrand disease • Hypoprothrombinemia/II · XIII · Dysfibrinogenemia

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